| Primary Identifier | MGI:3052104 | Allele Type | Targeted |
| Attribute String | Hypomorph | Gene | Myh10 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An arginine to cysteine mutation at amino acid 709 was inserted in exon 17 by homologous recombination. A floxed neo was inserted into intron 15. Southern blot and PCR confirmed recombination. Western blot indicated that this is a hypomorphic allele: expression in mutant brains was reduced 73% from wild-type levels. |
