Primary Identifier | MGI:3051853 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Grap2 |
Transmission | Germline | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 1-3, encompassing the majority of the transcript including the ATG, were replaced with a neomycin resistance gene via homologous recombination. Southern blot confirmed recombination. Intracellular staining of thymocytes confirmed lack of protein in mutants. |