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Allele : Ptprn2<tm1Aln> protein tyrosine phosphatase receptor type N polypeptide 2; targeted mutation 1, Abner Louis Notkins

Primary Identifier  MGI:3051779 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptprn2
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene replaced part of the 5' upstream promoter, exon 1 and part of intron 1, including the AUG start codon, 106 additional codons and a 5' UTR of at least 145 nucleotides. Northern blot indicated absence of transcript in brains of mutant mice. Further confirmation was provided by Western blot analysis showing lack of wild-type protein in brains of mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • IA-2Beta<->,
  • IA-2Beta<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

14 Publication categories

Trail: Allele