| Primary Identifier | MGI:3053109 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ly96 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector was designed to replace the first exon, encoding 37 amino acids, with a neomycin resistance gene. RT-PCR indicated homozygotes lacked mRNA in bone marrow-derived macrophages. Protein was not expressed on the cell surface as shown by staining with a mAB for the TLR4-Ly96 complex. |
