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Allele : Kcnma1<tm1Rwa> potassium large conductance calcium-activated channel, subfamily M, alpha member 1; targeted mutation 1, Richard W Aldrich

Primary Identifier  MGI:3053849 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kcnma1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted to flank exon 1. In addition, EGFP-FRT-flanked neomycin cassette was inserted 3' to exon 1. The floxed exon was removed by mating mutant animals to the cre deleter strain FVB/N-Tg(EIIa-cre)C5379Lmgd/J. Protein was undetectable by Western blot analysis of bladder proteins. The EGFP-neomycin cassette was not removed by Cre recombinase.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • KCa1.1<->,
  • Slo<->,
  • Slo<->,
  • KCa1.1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

35 Publication categories

Trail: Allele