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Allele : Nr5a2<tm1Auw> nuclear receptor subfamily 5, group A, member 2; targeted mutation 1, Johan Auwerx
Primary Identifier  MGI:3053912 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nr5a2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Amino acids 283-295, coded by exon 6, were replaced with an IRES-lacZ and neo cassette. Correct targeting was confirmed by Southern blot analysis. Quantitative PCR of heterozygotes showed a mean reduction of 40% in mRNA levels in the duodenum, ileum, and colon relative to wild-type mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • LRH-1<->,
  • LRH-1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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