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Allele : Tg(CD2-Il2rb)A-1Ttg transgene insertion A-1, Tadatsugu Taniguchi
Primary Identifier  MGI:3054884 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CD2-Il2rb)A-1Ttg
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A cDNA encoding mouse interleukin 2 receptor beta lacking amino acids 316 through 385 - the acidic (A-) region - of the extracellular domain of the mature protein was inserted into an expression vector containing 5 kb of 5' flanking sequence, including the promoter, transcription initiation site and first intron, and 5.5 kb of 3' flanking sequence including the locus control region (LCR) of the human CD2 gene. The CD2 promoter/enhancer direct expression in cells of the lymphoid lineage.
  • mutations:
  • Insertion
  • synonyms:
  • IL-2Rb A mutant,
  • Tg(CD2-Il2rb-deltaLeu316-Leu385)1Ttg,
  • IL-2Rbetac deltaA-mutant,
  • IL-2Rb A mutant,
  • Tg(Il2rb)A,
  • IL-2Rbetac deltaA-mutant,
  • Tg(CD2-Il2rb-deltaLeu316-Leu385)1Ttg,
  • Tg(Il2rb)A
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1 Feature

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Genome

1 Expresses

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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2 Publication categories

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