| First Author | Tu AY | Year | 1997 |
| Journal | Gene | Volume | 188 |
| Issue | 1 | Pages | 115-8 |
| PubMed ID | 9099868 | Mgi Jnum | J:39306 |
| Mgi Id | MGI:86689 | Doi | 10.1016/s0378-1119(96)00793-7 |
| Citation | Tu AY, et al. (1997) Characterization of the mouse gene encoding phospholipid transfer protein. Gene 188(1):115-8 |
| abstractText | The mouse gene encoding phospholipid transfer protein (PLTP) was cloned from 129/SvJ lambdaFIX(R) II library and characterized for the first time. It is comprised of 16 exons separated by 15 introns. Its gene organization strikingly resembles that encoding the human PLTP; the exon-intron junctions in these two genes are completely conserved. Sequencing analysis reveals that the putative promoter of mouse PLTP gene consists of a TATA-box, a high GC region, and several consensus sequences for the binding of transcription factors. Within the first 200 bp of the 5'-flanking region, the mouse and human PLTP genes share 81.1% identity of nt sequences and contain the consensus sequences for the transcription factors AP-2 and Sp1 at the same locations. |
