|  Help  |  About  |  Contact Us

Allele : Ret<tm1Mat> ret proto-oncogene; targeted mutation 1, Masahide Takahashi

Primary Identifier  MGI:3055332 Allele Type  Targeted
Gene  Ret Transmission  Germline
Strain of Origin  129X1/SvJ Is Recombinase  false
Is Wild Type  false
molecularNote  The introduction of a targeting vector resulted in two amino acid replacements, KLY1062 to KIF1062, within exon 19 and a floxed PGK-neo inserted into intron 19. RT-PCR indicated that the substitutions did not inhibit correct splicing in mutants, nor did the neo create significant differences in protein expression between mutant and wild-type mice.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Y1062F,
  • Y1062F,
  • c-Ret-KI<Y1062F>,
  • c-Ret-KI<Y1062F>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele