Primary Identifier | MGI:3055332 | Allele Type | Targeted |
Gene | Ret | Transmission | Germline |
Strain of Origin | 129X1/SvJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The introduction of a targeting vector resulted in two amino acid replacements, KLY1062 to KIF1062, within exon 19 and a floxed PGK-neo inserted into intron 19. RT-PCR indicated that the substitutions did not inhibit correct splicing in mutants, nor did the neo create significant differences in protein expression between mutant and wild-type mice. |