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Allele : Casr<Nuf> calcium-sensing receptor; nuclear flecks

Primary Identifier  MGI:3054788 Allele Type  Chemically induced (other)
Gene  Casr Inheritance Mode  Dominant
Strain of Origin  (C3H/He x 102/El)F1 Is Recombinase  false
Is Wild Type  false
description  Isopropyl methane sulfonate induced
molecularNote  This mutation was induced by treating a male mouse with isopropyl methane sulfonate. Sequencing revealed a missense T-to-A transversion in the fourth transmembrane domain, causing a leucine to glutamine substitution. Western blot showed a 167-kDa protein in both mutants and wild-types.
  • mutations:
  • Single point mutation
  • synonyms:
  • iPMS-112,
  • iPMS-112,
  • Nuf,
  • Nuf
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele