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Allele : Dysf<prmd> dysferlin; progressive muscular dystrophy

Primary Identifier  MGI:3055150 Allele Type  Spontaneous
Attribute String  Null/knockout Gene  Dysf
Inheritance Mode  Not Specified Strain of Origin  A/J
Is Recombinase  false Is Wild Type  false
molecularNote  A retrotransposon insertion occurred within intron 4, causing aberrant splicing of the gene. Protein was abolished as shown by Northern blot and immunoblot analysis. The insertion was 6000bp in size. This allele was found only in A/J mice, not in A/WySnJ, A/HeJ, C57BL/6J, SJL/J, SWR/J or 129/SvJ mice.
  • mutations:
  • Transposon insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

6 Carried By

Trail: Allele

0 Driven By

56 Publication categories

Trail: Allele