Primary Identifier | MGI:3055103 | Allele Type | Transgenic |
Attribute String | Reporter | Gene | Tg(CAG-EGFP)B5Nagy |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
description | In transgenic newborn and adult mice, the entire organ system expresses GFP. While transgene expression is ubiquitous, expression levels vary between organs. Cells and tissues with increased hemoglobin content exhibit reduced fluorescence as development progresses. |
molecularNote | The construct contains an enhanced green fluorescent protein gene driven by the CMV intermediate early enhancer coupled to the chicken beta actin promoter. The transgene integrated occurred on an unidentified autosome, and is expressed in all nucleated embryonic tissues. |