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Allele : Sh2b1<tm1Lr> SH2B adaptor protein 1; targeted mutation 1, Liangyou Rui

Primary Identifier  MGI:3055487 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sh2b1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The promoter region through the majority of the coding sequence was replaced with a neomycin resistance gene. All isoforms are predicted to be eliminated and immunoblot confirmed that no wild-type protein was present in mutant livers.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • SH2-B<->,
  • SH2-B<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

17 Publication categories

Trail: Allele