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Allele : Tg(Igk-C/Igk-V125)1Jwt transgene insertion 1, James W Thomas

Primary Identifier  MGI:3057119 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Igk-C/Igk-V125)1Jwt
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene encodes a light chain that, when co-expressed with a transgene encoding the heavy chain with the VDJ of mAB125, binds most mammalian insulins. The source of the immunoglobulin kappa chain VJ sequence in this transgene was the BALB/c IgG1 mouse anti-human insulin monoclonal antibody, mAb125 (from the American Type Culture Collection).
  • mutations:
  • Insertion
  • synonyms:
  • VK125-Ck,
  • VK125,
  • VK125,
  • Vk125Tg,
  • VK125-Ck,
  • Vk125Tg,
  • Vkappa125Tg,
  • Vkappa125Tg
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele