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Publication : Long-lasting actions of somatostatin on pyramidal cell excitability in the mouse cingulate cortex.

First Author  Riedemann T Year  2019
Journal  Neurosci Lett Volume  698
Pages  217-223 PubMed ID  30668961
Mgi Jnum  J:282551 Mgi Id  MGI:6364285
Doi  10.1016/j.neulet.2019.01.034 Citation  Riedemann T, et al. (2019) Long-lasting actions of somatostatin on pyramidal cell excitability in the mouse cingulate cortex. Neurosci Lett 698:217-223
abstractText  Many neurological diseases are related to disturbances of somatostatin- (SOM-) expressing interneurons in the cingulate cortex. Therefore, their role within the circuitry of the cingulate cortex needs to be investigated. We describe here the physiological time course of SOM effects onto pyramidal cell excitability and action potential discharge pattern. Furthermore, we show that the GRK2 inhibitor Gallein had no effect on the reduced SOM-induced response following repetitive SOM applications.
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