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Allele : Gt(ROSA)26Sor<tm1(Akt1/EGFP)Glas> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, David J Glass

Primary Identifier  MGI:3512295 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The HSA-driven CreERt2 transgene was inserted in cis with a cassette containing a constitutively active form of Atk1 fused to EGFP (c.a.Akt-EGFP). Prior to the addition of tamoxifen, the HSA promoter drives transctiption of CreERt2, with absence of c.a.Akt-EGFP transcription. Upon the addition of tamoxifen, CreERt2 expression would drive its own excision, leaving the c.a.Akt-EGFP cassette downstream of the HSA promoter.
  • mutations:
  • Insertion
  • synonyms:
  • Akt<Ind.Tg>,
  • c.a.Akt-EGFP,
  • Akt<Ind.Tg>,
  • c.a.Akt-EGFP
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele