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Allele : Sh2d1a<tm1Vei> SH2 domain containing 1A; targeted mutation 1, Andre Veillette

Primary Identifier  MGI:3512182 Allele Type  Targeted
Gene  Sh2d1a Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Using a knock-in strategy, arginine 78 in exon 3 was replaced by an alanine. Crossing with EIIa-Cre mice removed a floxed neo. The mutation had no effect on protein abundance.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • sap<R78A>,
  • sap<R78A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele