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Allele : Pbx3<tm1Mlc> pre B cell leukemia homeobox 3; targeted mutation 1, Michael L Cleary

Primary Identifier  MGI:3510441 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pbx3
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was replaced with a neomycin resistance gene in opposite transcription orientation. The deletion created an early frame-shift mutation that caused termination of the reading frame upstream of its dimerization and DNA binding domains. Western blot indicated a lack of protein in brains of mutants.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Pbx3<->,
  • Pbx3<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories

Trail: Allele