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Allele : Ly6a<tm2(RUNX1)Grau> lymphocyte antigen 6 family member A; targeted mutation 2, Timothy A Graubert

Primary Identifier  MGI:3510673 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence, Reporter Gene  Ly6a
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert human RUNX1 (CBFA2T1), IRES-EGFP and floxed PGK-neo into exon 2 of the endogenous gene. Expression of the inserted mRNA was detectable in peripheral blood leukocytes from heterozygous animals by RT-PCR. Flow cytometry indicated GFP was highly expressed in peripheral blood and bone marrow cells.
  • mutations:
  • Insertion
  • synonyms:
  • Ly6a<tm2Grau>,
  • Sca1<AML1-ETO ires EGFP>,
  • Sca1<AML1-ETO ires EGFP>,
  • Sca1<AE>,
  • Ly6a<tm2Grau>,
  • Sca1<AE>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele