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Allele : Rr169<tm2Rao> regulatory region 169; targeted mutation 2, Anjana Rao
Primary Identifier  MGI:3512141 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout Gene  Rr169
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked neomycin resistance gene cassette replaced a 1.9 kb section containing DNase I hypersensitivity site IV (HS IV), an Il4 silencer located between Il4 and Kif3a. Transient Cre recombinase expression removed the neo cassette in ES cells. DNase hypersensitivity analysis of mutant cells showed a loss of HS IV, but no disruption of the other hypersensitivity sites.
  • mutations:
  • Disruption caused by insertion of vector
  • synonyms:
  • Il4<tm2Rao>,
  • HS IV<->,
  • Il4<tm2Rao>,
  • HS IV<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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