Primary Identifier | MGI:3512421 | Allele Type | Transgenic |
Attribute String | Inducible, Inserted expressed sequence | Gene | Tg(tetO-BCL6)1Bbn |
Strain of Origin | CD-1 | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A human BCL6 gene is expressed by this transgene. Transcription is directed by a tetracycline-responsive promoter element (tetO). When bred with another transgenic mouse expressing tetracycline-controlled transactivator protein (tTA) to create a bitransgenic animal, BCL6 expression can be regulated with the tetracycline analog, doxycycline. This line of mice had approximately 4 copies of the transgene. |