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Allele : Map2<repro4> microtubule-associated protein 2; reproductive mutant 4, JAX Reproductive Mutagenesis Program

Primary Identifier  MGI:3512900 Allele Type  Chemically induced (ENU)
Gene  Map2 Inheritance Mode  Recessive
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
description  Males are infertile: very low testis weight, no epididymal sperm are recovered. Histological analysis shows arrest of spermatogenesis during late pachytene stage of meiotic prophase, some germ cells appear apoptotic.
molecularNote  This phenotypic mutant was identified in an ENU mutagenesis screen. A T to A transversion in an intron located between exons 2 and 3 in ENSMUST00000114015 and ENSMUST00000114017 transcripts, was confirmed by sequencing
  • mutations:
  • Single point mutation
  • synonyms:
  • G1-397-34,
  • repro4,
  • repro4,
  • G1-397-34
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

5 Publication categories