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Allele : Erbb2<tm4(Erbb2)Mul> erb-b2 receptor tyrosine kinase 2; targeted mutation 4, William J Muller
Primary Identifier  MGI:3521857 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Erbb2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to replace the first coding exon with the rat Erbb2 cDNA and a neo. Analysis of the RT-PCR product indicated that mutants only expressed the rat cDNA. Western blot showed a reduced level of protein was expressed compared to wild-type mice.
  • mutations:
  • Insertion
  • synonyms:
  • Erbb2<Erbb2>,
  • Erbb2<Erbb2>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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