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Allele : Irf6<Gt(OST398253)Lex> interferon regulatory factor 6; gene trap OST398253, Lexicon Genetics

Primary Identifier  MGI:3522096 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Irf6
Transmission  Germline Strain of Origin  129S5/SvEvBrd
Is Recombinase  false Is Wild Type  false
Project Collection  Lexicon
description  This mutation is present in Lexicon Genomics' gene trap-mutated ES cell line OST398253. It was generated in an unspecified 129/Sv-derived ES cell line by random insertion of the VICTR48 gene trap vector.
molecularNote  The gene trap vector VICTR48 inserted into intron 1, 36 bp from the splice donor site. The vector contained flanking long terminal repeats, splice acceptor and donor sites, the ORF for neo, stop codons, polyA signal, the PGK promoter, marker fusion transcript and OmniBank sequence tag fusion transcript. Protein was not detected in mutants by Western blot.
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • Irf6<Gt(VICTR48)1Bcsl>,
  • Irf6<gt1>,
  • Irf6<gt1>,
  • Irf6<Gt(VICTR48)1Bcsl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

24 Publication categories

Trail: Allele