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Allele : Macroh2a1<tm1Peh> macroH2A.1 histone; targeted mutation 1, John R Pehrson

Primary Identifier  MGI:3522572 Allele Type  Targeted
Attribute String  Null/knockout Gene  Macroh2a1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
description  ES cell line = 98-2 (Incyte Genomics; "129svJ").
molecularNote  An IRESBgeo cassette was inserted in 1st intron. This cassette was flanked by LoxP sites and a 3rd loxP site was inserted in the 2nd intron. Transient cre expression removed the floxed sequence, including exon 2, which encodes the first part of the H2A domain. Western blot analysis confirmed the absence of protein product.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • macroH2A1<->,
  • macroH2A1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele