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Allele : Aph1a<tm1Bdes> aph1 homolog A, gamma secretase subunit; targeted mutation 1, Bart De Strooper
Primary Identifier  MGI:3522625 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Aph1a
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  FRT-flanked PGK-hygro with a loxP site downstream and a lacZ sequence was inserted downstream of the gene in position 3444. A second loxP site was inserted into position 540 in intron 1. RT-PCR and Western blot of mutant MEFs demonstrated the expression of mRNA or protein, respectively.
  • mutations:
  • Insertion
  • synonyms:
  • Aph1A<flx>,
  • Aph1A<flx>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele




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