Primary Identifier | MGI:3525223 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Col2a1-Hdac4)1Eno |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Expression of a signal resistant mutant form of Hdac4 in which serines 246, 467, and 632 were replaced with alanines was driven by the a 3 kb fragment of the Col2a1 promoter and the Col2a1 3 kb chondrocyte-specific enhancer region. Expression of the transgene was seen in proliferating chondrocytes. |