| Primary Identifier | MGI:3526452 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Spred1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A PGK-neo cassette replaced much of exon 4, including the sequence encoding the kit-binding domain and Sprouty-related COOH-terminal cystein-rich domains. RT-PCR confirmed the lack of transcript in mutant brain samples, and Western blot showed the lack of protein in mutant brain, liver, and kidney samples. |