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Allele : Tg(Igh-6/Igh-V125)2Jwt transgene insertion 2, James W Thomas

Primary Identifier  MGI:3526723 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Igh-6/Igh-V125)2Jwt
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  This construct encodes an IgMa constant region with the variable specificity from BALB/c IgG1 mouse anti-human insulin monoclonal antibody, mAb125 that was the source of the immunoglobulin heavy chain VDJ sequence in this transgene. The resulting antibody binds insulin when co-expressed with a transgene encoding the light chain with the VJ of mAB125.
  • mutations:
  • Insertion
  • synonyms:
  • 125Tg,
  • VH125Tg,
  • VH Tg125,
  • 125VH,
  • 125HC,
  • 125Tg,
  • VH Tg125,
  • VH125,
  • VH125Tg,
  • VH125,
  • 125VH,
  • 125HC
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1 Feature

Trail: Allele

Genome

2 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

14 Publication categories

Trail: Allele