|  Help  |  About  |  Contact Us

Allele : Tg(RAB27A-EGFP/Rab27a)84Seab transgene insertion 84, Miguel C Seabra
Primary Identifier  MGI:3527487 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(RAB27A-EGFP/Rab27a)84Seab
Strain of Origin  (C57BL/6J x CBA/Ca)F2 Is Recombinase  false
Is Wild Type  false
description  Crosses of lines 84 and 90 with Rab27a mice rescue the ashen phenotype. This is a representative record representing Tg(RAB27A-EGFP/Rab27a)84Seab and Tg(RAB27A-EGFP/Rab27a)90Seab, both of which have identical expression patterns, and Tg(RAB27A-EGFP/Rab27a)82Seab which has an unspecified expression pattern.
molecularNote  This transgene contains a human RAB27A promoter, a fusion gene of EGFP and the mouse Rab27a gene followed by a polyadenlyation sequence. Fluorescence microscopy and immunoblot analysis showed expression of EGFP in lines 84 and 90 mimics the endogenous gene expression pattern.
  • mutations:
  • Insertion
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom