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Allele : Tg(ITGAM-HBEGF/EGFP)34Lan transgene insertion 34, Richard A Lang

Primary Identifier  MGI:3574313 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(ITGAM-HBEGF/EGFP)34Lan
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene contains a fusion product involving simian diphtheria toxin receptor and green fluorescent protein under the control of the human ITGAM (integrin alpha M) promoter (CD11b), and human growth hormone sequence. Mice carrying this transgene have a diphtheria toxin (DT) inducible system that transiently depletes macrophages. RT-PCR analysis of bone marrow macrophages detects specific transgene expression.
  • mutations:
  • Insertion
  • synonyms:
  • CD11b-DTR,
  • tg(CD11b-DTR)Llan,
  • tg(CD11b-DTR)Llan,
  • CD11b-DTR,
  • Tg(ITGAM-DTR/EGFP)34Lan,
  • Tg(ITGAM-DTR/EGFP)34Lan
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

83 Publication categories

Trail: Allele