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Allele : Tg(LPV-TAg121)#Tvd transgene insertion #, Terry Van Dyke

Primary Identifier  MGI:3531485 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(LPV-TAg121)#Tvd
Strain of Origin  (C57BL/6J X DBA/2)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene consists of a lymphotropic papovavirus (LPV) enhancer/early promoter and a mutant SV40 T antigen sequence truncated after amino acid 121 followed by 11 missense residues. The resulting protein includes the RB1-binding region but lacks the small t antigen and the TRP53 binding region. Regulatory sequences direct expression of the transgene in B- and T-lymphocytes and choroid plexus epithelium.
  • mutations:
  • Insertion
  • synonyms:
  • dl1137,
  • LST1137,
  • dl1137,
  • LST1137
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele