Primary Identifier | MGI:3574016 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(SOD1*G37R)29Dpr |
Strain of Origin | (C57BL/6J x C3H/HeJ)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A 12 kb genomic DNA fragment containing a mutated form of human SOD1 with a glycine to arginine substitution at amino acid 37 (G37R) was used for the transgene. The G37R mutation is found in some cases of familial amyotrophic lateral sclerosis (FALS). |