| Primary Identifier | MGI:3574926 | Allele Type | Targeted |
| Attribute String | Hypomorph | Gene | Slc26a2 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A C1184T transition was inserted into exon 3 to create an A386V substitution in the eighth transmembrane domain. A neo was inserted into intron 2. Northern blot of mutant skin samples indicated that the presence of the neo caused impaired splicing of exon 2 to exon 3, with an abnormal band comprising ~40 and 60% of the total transcript in hetero- and homozygous animals, respectively. |
