Primary Identifier | MGI:3574967 | Allele Type | Radiation induced |
Gene | T(16;17)43H | Strain of Origin | (C3H/HeH x 101/H)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This chromosome is a result of a reciprocal translocation with one breakpoint located within the centromeric heterochromatin of Chr16, and the other located in the B3 band of Chr17. In conjunction with a normal Chr16 and two normal Chr17s, the presence of this mutation results in segmental trisomy of the proximal 30 Mb of Chr17, which includes over 310 known genes, and monosomy for the tip of centromeric heterochromatin of Chr16. |