| Primary Identifier | MGI:3576122 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Grid2 |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP sequence and an Flp-flanked neo was inserted 381 bp upstream of exon 12 and a second loxP sequence was inserted downstream of exon 12. Exon 12 encodes the putative transmembrane segment M3. Crossing with Tg(EIF1A-flp)66Mim removed the neo. Western blot analysis demonstrated that protein expression in cerebellar homogenates from mutants was comparable to that of wild-type. |
