|  Help  |  About  |  Contact Us

Allele : Pfkfb3<tm1Jche> 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; targeted mutation 1, Jason Chesney

Primary Identifier  MGI:3576782 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pfkfb3
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct was designed to insert a neomycin cassette and a stop codon to replace exons 3-7, the sequence encoding the substrate binding site and magnesium binding site. RT-PCR of heterozygote lung samples showed a 50% decrease in transcript levels.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • iPFK2<->,
  • iPFK2<->
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele