| Primary Identifier | MGI:3576029 | Allele Type | Chemically induced (ENU) |
| Gene | Igf1r | Inheritance Mode | Recessive |
| Strain of Origin | A/J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This mutation, which was identified in an ENU mutagenesis screen, is due to a T-to-A transversion in exon 13 that introduces a premature stop codon upstream of the sequence encoding the transmembrane and kinase domains. Western blot analysis of protein extracts from homozygous mutant 18.5 dpc embryos and newborn mice detected no IGF1R protein. |
