| Primary Identifier | MGI:3577256 | Allele Type | Targeted |
| Gene | Dp(11Cops3-Rnf112)1Jrl | Transmission | Germline |
| Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The engineered chromosome bears a duplication of a ~3 Mb segment of Chr 11 containing 19 genes including Cops3 (a.k.a. Csn3), which only in the duplicate copy is interrupted (and inactivated) by an insertion; the entire coding region, but not the final, untranslated exon of Rnf112 (formerly Zfp179); and all the intervening DNA. The insertion in Cops3 contains a tyrosinase minigene and a transgene comprising wild-type agouti cDNA under control of the human keratin 14 promoter. |
