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Allele : Tg(Igk-Lta/Ltb)4Cys transgene insertion 4, Jason G Cyster

Primary Identifier  MGI:3577756 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Igk-Lta/Ltb)4Cys
Strain of Origin  (C57BL/6J x DBA/2J)F2 Is Recombinase  false
Is Wild Type  false
description  Of the several lines created, lines 4 and 10 both overexpressed the fusion gene on B cells but not on T cells.
molecularNote  A 450 bp DNA fragment of the Ltb gene coding the transmembrane and membrane-proximal region was fused to a 486 bp fragment of the Lta gene coding for the receptor binding domain. This chimeric construct was placed under the control of an Igk promoter.
  • mutations:
  • Insertion
  • synonyms:
  • kappaLTalpha,
  • kappaLTalpha
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1 Feature

Trail: Allele

Genome

2 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele