|  Help  |  About  |  Contact Us

Allele : Ptprc<tm1Tyb> protein tyrosine phosphatase receptor type C; targeted mutation 1, Victor L J Tybulewicz

Primary Identifier  MGI:3579087 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptprc
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 12, which encodes part of the extracellular domain and is common to all isoforms, was disrupted by the insertion of a neomycin resistance gene. Flow cytometry of splenocytes, lymphocytes, lymph node and bone marrow cells with an antibody recognizing all isoforms failed to detect protein on any cells.
  • mutations:
  • Insertion
  • synonyms:
  • Cd45<->,
  • Cd45<->
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele