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Allele : Mtor<tm1Clyn> mechanistic target of rapamycin kinase; targeted mutation 1, Christopher Lynch

Primary Identifier  MGI:3580054 Allele Type  Targeted
Attribute String  Not Specified Gene  Mtor
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 49 and a floxed neo cassette was inserted downstream of a modified exon 50. A point mutation at amino acid D2338 results in a kinases dead protein.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • FRAP1<TMICLYN>,
  • mTOR<flox>,
  • mTOR<flox>,
  • FRAP1<TMICLYN>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele