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Allele : Hnrnpu<Gt(U3Neo)1Rul> heterogeneous nuclear ribonucleoprotein U; gene trap 1, H Earl Ruley

Primary Identifier  MGI:3580289 Allele Type  Gene trapped
Attribute String  Hypomorph Gene  Hnrnpu
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  The gene trap vector inserted into an intron of the locus and resulted in alternative splicing to a cryptic 3' splice site located in the neo, creating a hypomorphic allele. The expected transcript would be 503 nt long, however, RT-PCR demonstrated that the major PCR product was only 93 nt long and did not hybridize to a U3 probe.
  • mutations:
  • Insertion of gene trap vector
  • cellLines:
  • 1B3
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele