| Primary Identifier | MGI:2449158 | Allele Type | Spontaneous |
| Gene | Vamp1 | Inheritance Mode | Recessive |
| Strain of Origin | C3H/HeSnJ | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A spontaneous mutant identified at The Jackson Laboratory. A c.190G>T transversion creates a premature stop codon at glutamic acid codon 64 (p.E64*). The predicted protein that results would lack both a transmembrane domain and a calmodulin interaction domain. mRNA levels are severely reduced and no protein can be detected by immunohistochemistry in the brain. |
