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Allele : Kdr<tm3.1Jrt> kinase insert domain protein receptor; targeted mutation 3.1, Janet Rossant

Primary Identifier  MGI:3583012 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout, Reporter Gene  Kdr
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of an in-frame lacZ gene and a loxP site flanked neomycin resistance gene cassette replaced the translated portion of the first coding exon and the proximal part of the next intron, and placed lacZ under the transcriptional control of the endogenous promoter. In addition, the 1st intronic enhancer (Rr176) was deleted. The floxed neo cassette was subsequently removed by crossing to cre-deleter mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Flk1LacZ (Del) neo out,
  • Flk1LacZ (Del) neo out,
  • Flk1-LacZ del Sw/B neo-out,
  • Flk1-LacZ del Sw/B neo-out
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele