| Primary Identifier | MGI:3582683 | Allele Type | Targeted |
| Attribute String | Modified isoform(s) | Gene | Gata1 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| description | Authors report phenotype similar to Gata1tm7Sho. |
| molecularNote | A loxP site was inserted into intron 1 and a neomycin resistance gene cassette with a loxP site was inserted into intron 2. The neo cassette and exon 2 were removed by transfecting a GFP-Cre plasmid followed by fluorescence-activated cell sorting for GFP+ cells. This allele emulates the N-terminally truncated human "s" isoform that is translated from the downstream ATG start codon in exon 3. |
