Primary Identifier | MGI:3583893 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Upk2-cre)6Xrw |
Strain of Origin | FVB/N | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A construct was generated having a 3.6 kb fragment of the mouse Upk2 promoter, cre recombinase and a polyA signal. The transgene was purified and microinjected into fertilized FVB/N oocytes. Three founder lines 4,5,6) were obtained, all showing germline transmission and urothelium-specific cre mRNA expression (not detected in any other tissues). Mice established from founder 6 were crossed to reporter mice to verify cre recombinase activity in the urothelium. |