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Allele : Polg<tm1Prol> polymerase (DNA directed), gamma; targeted mutation 1, Tomas A Prolla
Primary Identifier  MGI:3583920 Allele Type  Targeted
Attribute String  Not Specified Gene  Polg
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct was designed to introduce an AC to CT two-base substitution in positions 1054 and 1055, resulting in a critical residue substitution in the conserved exonuclease domain (D257A).
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • mtDNA-mutator,
  • Polg<tm1Tprol>,
  • PolgA<D257A>,
  • Polg<tm1Tprol>,
  • PolgA<D257A>,
  • Polg<m>,
  • Polg<m>,
  • Polg<A>,
  • Polg<A>,
  • mtDNA-mutator,
  • Polg<mut>,
  • Polg<mut>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

48 Publication categories

Trail: Allele




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