| Primary Identifier | MGI:3587748 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Klb |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Most of the putative exon 1 containing the first ATG was deleted upon the insertion of an EGFP with a loxP-flanked PGK-neo in reverse orientation. Northern blot and RT-PCR confirmed lack of transcript in mutant liver samples. Absence of protein was demonstrated by Western blot of mutant liver, white adipose tissue and kidney. |
