|  Help  |  About  |  Contact Us

Allele : Apc<tm1Kk> APC, WNT signaling pathway regulator; targeted mutation 1, Khashayarsha Khazaie

Primary Identifier  MGI:3589207 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Apc
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted to flank exons 11 and 12. Cre-mediated deletion of these exons would result in the out-of-frame splicing of exon 10 to exon 13 and the generation of a prematurely terminated 468-amino acid protein. This mutant protein would be shorter than most truncated Apc proteins.
  • mutations:
  • Insertion
  • synonyms:
  • Apc<lox468>,
  • Apc<lox468>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

23 Publication categories

Trail: Allele